Journal of Evolving Stem Cell Research · ISSN 2574-4372 · Open Access Pub
Aims and Scope
The journal publishes research on how stem cell identity is established, maintained and resolved — and on the experimental systems that make those processes measurable. Its remit follows the full title: stem cell science as a developing field, from mechanism through to carefully evaluated translation.
Aims
What the journal sets out to do
JESR exists to publish stem cell scholarship on its own terms: to report what a cell is and can become, how that was established, and what the evidence will and will not carry.
The journal welcomes work at every stage of that reasoning. A mechanistic result, a new or improved model system, a characterization or reporting study, and an early clinical observation are different kinds of contribution, and each is assessed against the standard appropriate to it rather than against a single expectation of clinical usefulness.
The journal asks that a manuscript be substantively about stem cells — their identity, potency, fate, regulation, or the systems used to study them — and that its conclusions match the evidence it presents.
Scope
Research the journal publishes
- Cell identity and state
- Molecular and functional definition of stem and progenitor states; markers, transcriptional and epigenetic state; how potency is established, maintained or resolved; heterogeneity within a population.
- Self-renewal and fate
- Signals, niches, constraints and timing that govern self-renewal and lineage commitment; fate mapping and lineage tracing; the regulatory programs that direct or restrict differentiation.
- Differentiation and reprogramming
- Directed differentiation and its protocols; induced pluripotency and cellular reprogramming; transdifferentiation; the reproducibility and characterization standards that make a derived cell type comparable between laboratories.
- Experimental systems and models
- Primary, pluripotent and progenitor culture; organoid and three-dimensional systems; reporter lines, genome editing and lineage-tracing tools; scaffolds and engineered microenvironments; disease modeling and in vitro systems used in pharmacology and toxicology.
- Stem cells in tissue and disease
- Stem and progenitor biology in development, homeostasis, injury and repair; cancer stem cell biology; hematopoiesis and other lineage-specific programs; the cellular basis of tissue failure.
- Methods, characterization and reporting
- Assay development and validation; quality control and authentication; computational and quantitative analysis of stem cell data; reporting practice and reproducibility studies, where the subject is substantively stem cell research.
- Carefully evaluated translation
- Preclinical and early clinical work with cell-based approaches, tissue engineering and regenerative strategies, published with the design that produced it stated plainly and with conclusions kept to what that design supports.
Deciding fit
How the journal reads a submission for scope
Within scope
- Stem or progenitor cells are the subject of the study, not an incidental material in it.
- The work reports mechanism, model development, characterization, method, or an evaluated application in which the stem cell biology is doing the explanatory work.
- Foundational and mechanistic studies with no immediate application, presented as such.
- Negative or confirmatory results that carry mechanistic or methodological insight.
- Computational and quantitative studies of stem cell systems supported by appropriate data or validation.
Outside scope
- General cell biology in which stem cells appear only incidentally or by mention.
- Work whose conclusions exceed the design, sample or system that produced them.
- Studies without the ethical approvals and consent that stem cell research requires.
- Manuscripts whose claims cannot be assessed because methods or characterization are not reported in reconstructible form.
The question editors ask first. Would removing the stem cell component leave the study intact? If it would, the work belongs in a journal of the discipline that remains. If it would not, the manuscript is in scope, and the remaining assessment is about evidence rather than subject.
Clinical usefulness, novelty and immediate therapeutic promise are not scope conditions. A study is not excluded for being fundamental, and it is not admitted for being applied.
Formats
Article types the journal accepts
Work within the scope above is published in one of four formats.
- Original Research
- Full-length investigations presenting new findings.
- Technical Advances
- New methods, protocols or technologies that extend what can be measured or made.
- Review Articles
- Analyses that synthesize a body of published work.
- Clinical Studies
- Translational and clinical work with cell-based approaches.
Word, abstract and reference limits for each type are set out in the Instructions for Authors.
Disciplines represented
The fields this work comes from
Stem cell science is worked on from several directions, and the journal's readership and board reflect that. Submissions are welcome from any of them where the subject is stem cell biology.
- Cell and developmental biology
- Molecular biology and genomics
- Hematology and immunology
- Cancer biology
- Neuroscience
- Tissue engineering and biomaterials
- Pharmacology and toxicology
- Bioinformatics and quantitative biology
- Regenerative and translational medicine
Before you submit
Check the requirements, then send the manuscript
Editorial decisions are based on scope, scientific quality, methodological rigor, ethical compliance, reporting quality, and relevance to the journal. The author instructions state what a manuscript must contain; the editorial policies state the ethical and integrity requirements that apply to stem cell research.
Instructions for Authors Editorial Policies Archive About the Journal